Breeding of the INS-GAS strain
Purpose of the experiment: Keeping INS-GAS transgenic mouse strain
Expected distress for the animals: Minimal distress. Lifespan of INS-GAS mice is usually more than 2 years.
Expected scientific or societal benefit: Spontaneous gastric inflammation and tumor.
How many and what kind of animals to be used: 200 INS-GAS mice
How demands for replacement, reduction and improvement will be adhered to: No demands as this is a unique model that mimics gastric mucosa, hypertrophy, hyperplasia, dyspepsia and tumor in humans.
Expected distress for the animals: Minimal distress. Lifespan of INS-GAS mice is usually more than 2 years.
Expected scientific or societal benefit: Spontaneous gastric inflammation and tumor.
How many and what kind of animals to be used: 200 INS-GAS mice
How demands for replacement, reduction and improvement will be adhered to: No demands as this is a unique model that mimics gastric mucosa, hypertrophy, hyperplasia, dyspepsia and tumor in humans.